Watch for Statin Interactions With Pradaxa
February 2017
New concerns will crop up about an interaction with simvastatin or lovastatin and the direct oral anticoagulant (DOAC), Pradaxa (dabigatran).
These combos seem to increase bleeding risk.
Simvastatin or lovastatin might increase Pradaxa absorption and drug levels by inhibiting P-glycoprotein...a transporter protein that pumps drugs out of cells and into the gut, urine, or bile for excretion.
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